Wito Richter Selected Research

YM 976

10/2020	Inhibition of type 4 cAMP-phosphodiesterases (PDE4s) in mice induces hypothermia via effects on behavioral and central autonomous thermoregulation.
1/2020	PAN-selective inhibition of cAMP-phosphodiesterase 4 (PDE4) induces gastroparesis in mice.

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Wito Richter Research Topics

Disease

3	Cystic Fibrosis (Mucoviscidosis) 01/2022 - 04/2007
3	Vomiting 12/2021 - 09/2013
3	Nausea 12/2021 - 09/2013
3	Infections 01/2021 - 01/2020
3	Heart Failure 02/2015 - 10/2005
2	Cardiomegaly (Heart Hypertrophy) 02/2015 - 10/2009
2	Ventricular Tachycardia 10/2012 - 07/2011
2	Cardiac Arrhythmias (Arrythmia) 10/2012 - 10/2005
1	Asthma (Bronchial Asthma) 01/2022
1	Inflammation (Inflammations) 01/2022
1	Respiratory Tract Diseases (Respiratory Tract Disease) 01/2022
1	Acute Lung Injury 01/2021
1	Hypothermia 10/2020
1	Gastroparesis 01/2020
1	Carney Complex 03/2014
1	Cognitive Dysfunction 09/2013
1	Ventricular Premature Complexes (Premature Ventricular Contraction) 10/2012
1	Aortic Valve Stenosis (Aortic Stenosis) 10/2009
1	Diarrhea 04/2007
1	Lung Diseases (Lung Disease) 06/2005

Drug/Important Bio-Agent (IBA)

4	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 01/2022 - 10/2009
4	Phosphodiesterase 4 InhibitorsIBA 12/2021 - 06/2005
3	Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA 01/2022 - 04/2007
3	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 01/2022 - 10/2012
2	3',5'-Cyclic-AMP Phosphodiesterases (3',5' Cyclic Nucleotide Phosphodiesterase)IBA 01/2021 - 01/2020
2	YM 976IBA 10/2020 - 01/2020
2	Protein Isoforms (Isoforms)IBA 09/2013 - 10/2012
2	Adrenergic Agents (Adrenergic Drugs)IBA 10/2012 - 10/2009
2	Cyclic NucleotidesIBA 10/2009 - 06/2005
1	Ion Channels (Ion Channel)IBA 01/2022
1	Adenosine (Adenocard)FDA LinkGeneric 01/2022
1	Peptides (Polypeptides)IBA 01/2022
1	A-factor (Streptomyces)IBA 01/2021
1	Isoflurane FDA LinkGeneric 01/2021
1	Interleukin-6 (Interleukin 6)IBA 01/2021
1	CytokinesIBA 01/2021
1	RolipramIBA 10/2020
1	edema factorIBA 01/2020
1	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 02/2015
1	Chloride Channels (Chloride Channel)IBA 02/2014
1	Phosphatidylinositols (Phosphatidylinositol)IBA 10/2012
1	CatecholaminesIBA 10/2012
1	CalciumIBA 10/2012
1	Isoproterenol (Isoprenaline)FDA LinkGeneric 07/2011
1	Proteins (Proteins, Gene)FDA Link 03/2011
1	salicylhydroxamic acid (SHAM)IBA 10/2009
1	diethylstilbestrol monophosphate (PDES)IBA 10/2009
1	Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)IBA 10/2005
1	Type 4 Cyclic Nucleotide PhosphodiesterasesIBA 10/2005

Therapy/Procedure

1	Induced Hypothermia 12/2021
1	Anesthesia 01/2021
1	Intraperitoneal Injections 07/2011
1	Catheters 07/2011